MSE Undergraduate Research Program Invited Talk
Friday, August 26, 2011
Paul G. Allen Auditorium (CIS-X 101)
Lecture at 3:30PMBioinspired Soft Materials to Direct Stem Cell Function and Tissue Regeneration
Kevin E. Healy
Jan Fandrianto Distinguished Professor in Engineering
Departments of Materials Science and Engineering, and Bioengineering
University of California at Berkeley
Highly regulated signals in the stem cell microenvironment, such as growth factor presentation and concentration, matrix stiffness, and ligand adhesion density have been implicated in modulating stem cell proliferation and maturation. Therefore, it is desirable to have independent control over both the biochemical and mechanical cues presented to cells to analyze their relative and combined effects on stem cell function. Accordingly, we have developed synthetic hydrogels and biointerfaces to assess the effects of adhesion ligand presentation and material moduli spanning physiologically relevant ranges (10 to 10,000 Pa) on stem cell function. Employing these soft materials, we have demonstrated that the mechanical and biochemical properties of a stem cell microenvironment can be tuned to regulate the self-renewal and differentiation of different types of stem cells including human embryonic, neural, and mesenchymal stem cells. We have further modified these tunable biomimetic hydrogels with matrix metalloproteinase labile crosslinkers (e.g. MMP-2, 9 &13), to be used as an assistive microenvironment for transplantation of stem cells into diseased or damaged tissue such as the infracted myocardium. These biomimetic hydrogels provide a foundation for systematic development of "pro-survival" microenvironments for cell transplantation and the potential improvement in the long-term results of regenerative therapies. Various examples from our work will be discussed during this presentation.
MSE Undergraduate Summer Research Poster Symposium
Science and Technology at the Nanoscale
Friday, August 26, 2011
CIS-X Patio
4:30PMAfter the invited talk by Prof. Kevin Healy
Sponsored by the Office of the Vice Provost for Undergraduate Education (VPUE)
* Pizza and drinks will be served*
#
Student Name
Advisor
Project Name
1
Dustin Barfield
N. Melosh
Photon-enhanced Thermionic Emission
2
Jena Barnes
R. Sinclair
FIB and SEM of Nanomaterials
3
Sy Bohy
A. Salleo
Transparent Electrodes and Applications for Al and Ga Doped Zinc Oxide Nanowires
4
Mai Bui
R. Dauskardt
Effect of Sunscreen on UV Damage of Human Stratum Corneum
5
Thomas Carney
Y. Cui
Surface Engineering of SnO Nanofibers for High Capacity Lithium Ion Batteries
6
Alice Che
M. McGehee
Effect of Using Chlorinated ITO for Polymer Solar Cells
7
Kevin Chow
A. Salleo
Ultraviolet Curing Process for Indium Oxide Thin-Film Transistors
8
Ben Cohn
S. Doniach
Simulation of Local-Ordered Glasses to Practice Intensity Correlation Techniques
9
Jo-Ann Deasis
R. Dauskardt
Mechanical Behavior of Macroporous Hybrid Organic-Inorganic Thin Films
10
Justin Doanne
J. Dionne
The Path to Plasmon-Enhanced Upconversion Using Ag Nanoprisms
11
Nick Hartley
A. Lindenberg
Examining Ultrashort Laser Pulses and Photon Emission at Plasma Filament Intersections
12
Olivia Isaac
N. Melosh
Electroporation to Improve Nanostraw Penetration in Cells
13
Pao Jirakulpattana
M. McGehee
Organic Solar Cells
14
Kyle Johnson
S. Heilshorn
Diffusion Characterization of RGD Elastin Hydrogels
15
Zoe Kaufman
P. McIntyre
Annealing Effects on Nano-Structured Ir/TiO2/Si/Al Anode Efficiency
16
Kendrick Kho
W. Nix
Size Dependence of the Mechanical Properties of hcp Zinc Nanopillars
17
Maxwell Kim
S. Heilshorn
Designing a Protein-Engineered, Nanofibrous Scaffold for Tissue Engineering
18
Richard Lee
M. Brongersma
Investigating Si Nanowires for Solar-Driven Water Splitting
19
Janina Motter
B. Cui
Upconversion Nanoparticles for Biological Applications
20
Eric Newton
P. McIntyre
Electrochem. Cell for Photo-Illumination of Nanostructured Anodes for H2O Oxidation
21
Karina Padilla
S. Heilshorn
Biotemplating of 2D and 3D Nanostructures
22
Dieter Rutzen
S. Wang
Magnetic Separation with a Microfabricated Magnetic Sifter
23
Jacob Sander
R. Sinclair
FIB and SEM of Nanomaterials
24
Jacob Smith
S. Wang
Optimization of TiO2 Synthesis for Magnetic Nanoparticle Application
25
Arianna Wee
R. Sinclair
Characterizing Gold Nanoparticles in Macrophages
Chris EarhartActing Assistant Professor
Materials Science & Engineering
Stanford University
496 Lomita Mall, Durand Building, Rm #131
Stanford, CA 94305-4034
Phone: 650-723-1284
Friday, August 26, 2011
REMINDER - MSE Colloquium and Poster Symposium - TODAY at 3:30PM (Pizza and Drinks after talk)
On Mon, Aug 22, 2011 at 2:23 PM, Chris Earhart <cearhart@stanford.edu> wrote:
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment